Brain shrinkage seen in those taking antipsychotic medications
A new study finds that one the fastest-growing classes ofprescription drugs in the United States is linked to shrinkage in the brains of those who take it, raising some new questions about the widening use of antipsychotic medications.
What they found was that those whose treatment with antipsychotic medication was most “intensive”—those who took the largest doses over the longest time–had the greatest losses in brain volume. The intensity of a subject’s antipsychotic medication therapy was a far stronger predictor of brain-volume loss than was the severity of his or her psychiatric symptoms or of the extent of his or her illicit drug or alcohol abuse, the researchers found.