ADHD drugs linked to heart disease and death

A major study recently published in the journal Pediatrics — and republished by countless other medical and mass media sources — made the bold claim that stimulant drugs like those used to treat attention deficit hyperactivity disorder (ADHD) in children are not linked to cardiovascular events and death. But a recent analysis by Dr. Robert Tozzi writing for FOX News explains that the study was flawed, and that the drugs will cause cardiovascular events or death, especially in individuals with certain conditions.

Like most studies that allege the safety of pharmaceutical drugs, the Pediatrics study was at least partially, if not completely, funded by the drug industry. It was also deliberately constructed in such a way as to artificially minimize the risks associated with stimulant drugs. As a result, its findings ended up mirroring claims long made by the drug industry that stimulant drugs are safe, and that children do not need to be tested for certain conditions prior to being prescribed them.

Claim: J&J Wrongly Marketed Antipsychotic Drug Risperdal to Kids

The FDA told Johnson & Johnson (JNJ) in 1997 that its request to market the antipsychotic drug Risperdal for children was “without any justification.” In the following years, J&J’s army of pharmaceutical sales reps made 100,000 sales calls on child and adolescent psychiatrists, justifying this by “qualifying” the docs if they had as few as one adult patient exhibiting signs of schizophrenia, according to a lawsuit.

It was a distinction only a lawyer can love, and now the Massachusetts attorney general is using it against J&J and its Janssen unit, alleging that J&J’s promotion of Risperdal for children was misleading.

Attorney General Alleges Jansen Illegally Marketed Antipsychotic Drug – to kids and the elderly

Drug manufacturer Ortho-McNeil-Janssen is being sued by Attorney General Martha Coakley for illegally marketing Risperdal, an atypical antipsychotic medication. The complaint, filed this week in Suffolk Superior Court, further alleges that Janssen failed to disclose serious risks associated with Risperdal’s use, including the risk of excessive weight gain, diabetes and, for elderly dementia patients, an increased risk of death.

DSM 5 Will Further Inflate The ADD Bubble

We are already in the midst of a false epidemic of ADD. Rates in kids that were 3-5% when DSM IV was published in 1994 have now jumped to 10%. In part this came from changes in DSM IV, but most of the inflation was caused by a marketing blitz to practitioners that accompanied new on-patent drugs amplified by new regulations that also allowed direct to consumer advertising to parents and teachers. In a sensible world, DSM 5 would now offer much tighter criteria for ADD and much clearer advice on the steps needed in its differential diagnosis. This would push back ,however feebly, against the skilled and well financed drug company sell. DSM 5 should work hard to improve its text, not play carelessly with the ADD criteria in a way that may unleash a whole set of dreadful unintended consequences- unneeded medication, stigma, lowered expectations, misallocation of resources, and contribution to the illegal secondary market peddling stimulants for recreation or performance enhancement.

The DSM 5 child and adolescent work group has perversely gone just the other way. It proposes to make an already far too easy diagnosis much looser.

How Did These Babies Die? Question unites grieving families

Matthew Schultz was only 2.5 hours old when he died on Feb. 21, 2009. A coroner’s report stated there was no anatomical or toxicological cause of death, which was deemed “natural”. Another baby, Greyson Rawkins, was only two months old when he died on March 23 of this year. A coroner’s report found Greyson died of sudden unexplained death in infancy and his death was ruled undetermined. However, the mothers of both babies were taking Effexor while carrying and believe the antidepressant drug may be connected to the deaths of their children. And, as KTW learned, there are widespread medical warnings about pregnant women taking antidepressants.