Zyprexa Drug Warnings:

There have been 25 drug regulatory agency warnings from seven countries (Australia, Canada, Denmark, New Zealand, South Africa, United Kingdom and United States) on Zyprexa (or olanzapine). These include the following (note that some warnings cite more than one side effect, so the list below may not be equal to the total number of warnings):

6 warnings on Zyprexa causing cardiovascular disorders
5 warnings on Zyprexa causing death or increased risk of death
3 warnings on Zyprexa causing weight gain
3 warnings on Zyprexa causing nervous system disorders
3 warnings on Zyprexa causing stroke
2 warnings on Zyprexa causing heart problems
2 warnings on Zyprexa causing blood disorders
2 warnings on Zyprexa causing metabolic disorders
2 warnings on Zyprexa causing muscle problems
2 warnings on Zyprexa causing blood pressure changes or high or low blood pressure
2 warnings on Zyprexa causing allergic reactions
2 warnings on Zyprexa causing skin conditions
1 warning on Zyprexa causing involuntary movements
1 warning on Zyprexa causing liver problems
1 warning on Zyprexa causing newborn complications (including infant withdrawal symptoms)
1 warning on Zyprexa causing sleep problems
1 warning on Zyprexa causing diabetes
1 warning on Zyprexa causing risk of fractures
1 warning on Zyprexa causing Neuroleptic Malignant Syndrome (a life-threatening neurological disorder)
1 warning on Zyprexa causing sexual dysfunction
1 warning on Zyprexa causing sedation

Zyprexa Drug Studies:

There have been 64 studies done in 17 countries (Australia, Bosnia and Herzegovina, Brazil, Canada, China, Denmark, France, Italy, Japan, Malaysia, Netherlands, Spain, Switzerland, Taiwan, Turkey, United Kingdom and United States) on Zyprexa (or olanzapine). These include the following (note that some studies cite more than one side effect, so the list below may not be equal to the total number of studies):

16 studies on Zyprexa causing cardiovascular disorders
15 studies on Zyprexa causing death or increased risk of death
12 studies on Zyprexa causing weight gain
8 studies on Zyprexa causing diabetes
7 studies on Zyprexa causing heart problems
6 studies on Zyprexa causing metabolic disorders
4 studies on Zyprexa causing nervous system disorders
4 studies on Zyprexa causing involuntary movements
3 studies on Zyprexa causing heart attacks
3 studies on Zyprexa causing stroke
3 studies on Zyprexa causing blood pressure changes or high or low blood pressure
2 studies on Zyprexa causing lack of efficacy
2 studies on Zyprexa causing skin conditions
2 studies on Zyprexa causing pregnancy complications
2 studies on Zyprexa causing sedation
2 studies on Zyprexa causing newborn complications
2 studies on Zyprexa causing Neuroleptic Malignant Syndrome (a life-threatening neurological disorder)
2 studies on Zyprexa causing cognitive impairment
1 study on Zyprexa causing pneumonia
1 study on Zyprexa causing muscle problems
1 study on Zyprexa causing lowered bone mass
1 study on Zyprexa causing premature birth
1 study on Zyprexa causing infant withdrawal symptoms
1 study on Zyprexa causing brain shrinkage or other structural brain changes
1 study on Zyprexa causing birth defects
1 study on Zyprexa causing suicide risk or completed suicide
1 study on Zyprexa causing swelling
1 study on Zyprexa causing risk of fractures
1 study on Zyprexa causing sexual dysfunction
1 study on Zyprexa causing Parkinson’s Disease
1 study on Zyprexa causing reproductive system disorders
1 study on Zyprexa causing blood disorders
1 study on Zyprexa causing mania or psychosis

Adverse Reaction Reports Filed with the US FDA: There have been 14,613 adverse reactions reported to the US FDA in connection with Zyprexa (olanzapine).

The FDA estimates that less than 1% of all serious events are ever reported to it, so the actual number of side effects occurring are most certainly higher.

• 2,747 cases of diabetes mellitus
• 1,943 cases of weight increased
• 1,036 cases of hypertension (high blood pressure)
• 1,032 cases of pancreatitis (inflammation of the pancreas)
• 911 cases of overdose
• 856 cases of hyperglycaemia (high blood sugar)
• 796 cases of death
• 721 cases of blood triglycerides increased
• 635 cases of diabetic ketoacidosis (build up of the chemical ketone in the blood)
• 597 cases of metabolic disorder

Documented Side Effects of Zyprexa:
Source: Physicians Desk Reference, National Institutes of Health’s Medline Plus, and/or the drug label.